Hi Robin,
it seems to me that when we activate the option for Touptek in camera settings to allow manual control of conversion gain via read mode , the histogram helper does not use the correct sensor analysis , in my example (I have a 2600M) I was set on LCG and it was using HCG sensor data or something else (maybe the ATR585M I was using before). It did not take the 2600M 16 bit low level noise I was expected. Disabling the option in camera setting and restarting SC did the job and I got then the correct sensor analysis. I have already seen that behaviour in SC 4.1
Kind regards
Olivier